Born and raised in San Jose, California, Anjelah Johnson is of Mexican and Native American descent. She became an internet sensation with her viral video "Nail Salon" and later, she appeared on "MADtv" as a series regular, which then spawned another internet sensation "Bon Qui Qui." Johnson was nominated for an ALMA Award for her work on the show.
Johnson can also be seen as a live action character in the film ALVIN AND THE CHIPMUNKS: THE SQUEAKQUEL alongside Jason Lee and the voices of Justin Long, Anna Faris and Amy Poehler. In 2010, Johnson starred in OUR FAMILY WEDDING. The film also stars Carlos Mencia, Regina King, and Oscar winner Forest Whitaker.
Johnson currently resides in Los Angeles and continues to tour with her stand up show in various cities around in the US.